Significant Changes to IACUC-Approved Protocols - August 2016


  • Provide IACUC members with a basic understanding as to what constitutes a significant change to an IACUC-approved protocol.
  • Allow IACUC members to gain an understanding of the review methods available to them for review and approval of significant changes
  • Empower the IACUC to implement the Veterinary Verification and Consultation (VVC) process at their institution


  • Define significant changes
  • Describe the review methods for significant changes
  • Formulate a template process to implement Veterinary Verification and Consultation (VVC)

Module Developers: Tim Allen, Mike Andrews, Javier Cisneros, Claire Hankenson, Rachel Murray

Module Materials
Slides (PPT) - UPDATED 10/12/2017 (Powerpoint - 845.47 KB)
Module Question

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