(PHS Policy IV.A.1.a.-i.)
- the designation of a different individual as the Institutional Official;
- administrative modifications that affect the reporting channels of the IACUC, the institutional official, or the veterinarian;
- modifications to IACUC procedures;
- change in the veterinarian designated as having program authority;
- change in the veterinarian's authority or responsibility;
- modifications to the occupational health program or the training program; and
- changes in the species or approximate numbers of animals housed at the institution.